(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(benzyloxycarbonylamino)propanoic acid
3-{[(benzyloxy)carbonyl]amino}-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine
CAS: 204316-36-9
Molecular Formula: C26H24N2O6
(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(benzyloxycarbonylamino)propanoic acid - Names and Identifiers
| Name | 3-{[(benzyloxy)carbonyl]amino}-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine |
| Synonyms | Fmoc-Dap(Z)-Oh Fmoc-Dap(Z)-OH Fmoc-L-Dap(Cbz)-OH Nα-FMoc-Nβ-Z-L-2,3-diaMinopropionic acid FMoc-N3-Cbz- L-2,3-diaMinopropionic acid FMoc-Dap(Z)-OH(Na-FMoc-N3-Z-2,3-DiaMinopropionic acid) FMoc-Dap(Z)-OH N-α-FMoc-N-β-Z-L-2,3-diaMinopropionic acid Fmoc-3-(Z-amino)-L-alanine, Nα-Fmoc-Nβ-Z-L-2,3-diaminopropionic acid 3-{[(benzyloxy)carbonyl]amino}-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(benzyloxycarbonylamino)propanoic acid (2S)-3-{[(benzyloxy)carbonyl]amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid |
| CAS | 204316-36-9 |
| EINECS | 1533716-785-6 |
| InChI | InChI=1/C26H24N2O6/c29-24(30)23(14-27-25(31)33-15-17-8-2-1-3-9-17)28-26(32)34-16-22-20-12-6-4-10-18(20)19-11-5-7-13-21(19)22/h1-13,22-23H,14-16H2,(H,27,31)(H,28,32)(H,29,30)/t23-/m0/s1 |
(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(benzyloxycarbonylamino)propanoic acid - Physico-chemical Properties
| Molecular Formula | C26H24N2O6 |
| Molar Mass | 460.48 |
| Density | 1.320±0.06 g/cm3(Predicted) |
| Melting Point | 119 °C |
| Boling Point | 723.0±60.0 °C(Predicted) |
| Flash Point | 391°C |
| Vapor Presure | 6.13E-22mmHg at 25°C |
| pKa | 3.57±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.623 |
(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(benzyloxycarbonylamino)propanoic acid - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29242990 |
(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(benzyloxycarbonylamino)propanoic acid - Introduction
3-{[(benzyloxy)carbonyl]amino}-N-[(9h-fluoren-9-ylmethyloxy) carbonyl]-L-alanine is an organic compound with a fluorene ring, benzyl and 2,3-diaminopropionic groups.
This compound is usually a white solid with a high melting point. It can be dissolved in some organic solvents, such as dimethyl sulfoxide and chloroform.
3-{[(benzyloxy)carbonyl]amino}-N-[(9h-fluoren-9-ylmethyloxy) carbonyl]-L-alanine have important uses in several fields. It is an important chiral ligand and can be used as a ligand in metal catalysts for Chiral synthesis reactions. In addition, it can also be used in the synthesis of pharmaceutical intermediates.
3-{[(benzyloxy)carbonyl]amino}-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine can be prepared by various methods. A common synthesis method is to react fluorenecyl chloride and benzoyl chloride with 2,3-diaminopropionic acid under basic conditions to generate 3-{[(benzyloxy)carbonyl]amino}-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine. The yield can be adjusted by controlling the reaction temperature, the reaction time, and the molar ratio of the reactants, among other factors.
For safety information, 3-{[(benzyloxy)carbonyl]amino}-N-[(9h-fluoren-9-ylmethyloxy) carbonyl]-L-alanine is less toxic and less dangerous. However, during handling and use, it is still necessary to pay attention to personal protective measures, such as wearing gloves, goggles and protective clothing. When used in a laboratory environment, it is necessary to observe appropriate laboratory practices and follow relevant waste disposal guidelines. When stored, it should be kept in a dry and well-ventilated place, away from fire and flammable materials.
This compound is usually a white solid with a high melting point. It can be dissolved in some organic solvents, such as dimethyl sulfoxide and chloroform.
3-{[(benzyloxy)carbonyl]amino}-N-[(9h-fluoren-9-ylmethyloxy) carbonyl]-L-alanine have important uses in several fields. It is an important chiral ligand and can be used as a ligand in metal catalysts for Chiral synthesis reactions. In addition, it can also be used in the synthesis of pharmaceutical intermediates.
3-{[(benzyloxy)carbonyl]amino}-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine can be prepared by various methods. A common synthesis method is to react fluorenecyl chloride and benzoyl chloride with 2,3-diaminopropionic acid under basic conditions to generate 3-{[(benzyloxy)carbonyl]amino}-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine. The yield can be adjusted by controlling the reaction temperature, the reaction time, and the molar ratio of the reactants, among other factors.
For safety information, 3-{[(benzyloxy)carbonyl]amino}-N-[(9h-fluoren-9-ylmethyloxy) carbonyl]-L-alanine is less toxic and less dangerous. However, during handling and use, it is still necessary to pay attention to personal protective measures, such as wearing gloves, goggles and protective clothing. When used in a laboratory environment, it is necessary to observe appropriate laboratory practices and follow relevant waste disposal guidelines. When stored, it should be kept in a dry and well-ventilated place, away from fire and flammable materials.
Last Update：2024-04-09 20:02:46
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